Assessment of Post-Concussion Syndrome

In the tests described next, scores are statistically compared to large databases of people with no mental health disorders or history of head injuries. The tests have been published and validated in peer reviewed scientific journals and are suitable for use in diagnostic systems. Together they can provide convergent evidence of an organic basis for a post-concussion syndrome, which requires specialised treatment with Neurotherapy [33] and appropriate nutrients to repair damaged tissues.

Quantitative Electroencephalography (QEEG)

QEEG of TBI patient
QEEG Mapping

QEEG is the statistical evaluation of the electrical activity of the brain.  The QEEGs of hundreds of typically functioning people with no mental health issues or history of head injuries make up the normative database against which the QEEG of patients are compared. The differences are expressed as Z scores (standardised deviations from th mean). QEEG is particularly suitable for the evaluation of post-concussion syndrome, as it is empirical, objective, non-intrusive and has been shown to be highly accurate in identifying and discriminating various neurophysiological patterns of brain dysfunction associated with Minor TBI and post-concussion syndrome [33-35]. 

A 2004 review of the scientific literature by Dr. Jacques Duff, published in the journal of the EEG and Clinical Neuroscience Society suggests that QEEG is superior to structural Neuroimaging techniques in detecting brain dysfunction related to Minor TBI and post-concussion syndrome [33] which can occur with or without loss of consciousness.

Traumatic Brain Injury Discriminant Analysis

TBI discriminant function
TBI Probability Index

The Traumatic Brain Injury probability index provides a statistical probability that the person has suffered a mild traumatic brain injury [35]. The QEEGs of Hundreds of people with head injuries from Veteran Affairs Hospitals in the US were analysed and a discriminant function was developed that reliably separated those people with head injuries from those without. The index provides independent evidence to support the conclusion of an organic basis for symptoms of post-concussion syndrome [35]

There are in excess of 40,000 QEEG papers published since 1990, and there are no concerns in these papers about false negatives from QEEG Discriminant Functions. The only negatively critical paper about the clinical uses of QEEG was published in 1997 by Newer from the Academy of Neurology. The opinions expressed in that paper were refuted and discredited by the EEG and Clinical Neuroscience Society [36] as they were shown to be based solely on innuendo and vague unsupported statements, without a comprehensive review of the extensive literature. Since then, the QEEG Neuroguide system used in the diagnosis of Post-concussion Syndrome has been approved by the US Food and Drug Administration (FDA) on the basis of its efficacy.

Low Resolution Electromagnetic Tomography (LORETA)

LORETA TBI
LORETA at 4Hz in patient with PCS

 

 

 

 

 

 

 

 

IntegNeuro Neurocognitive Test battery

IntegNeuro touchscreen
Integ Neuro
IntegNeuro is a comprehensive Neuropsychological test battery developed by the Brain Resource Company. It is an easy to use, fully automated and computer administered series of 14 separate neuropsychological cognitive tests (tests of mental functioning) that reflect an individual’s cognitive performance profile. The test battery draws on the Brain Resource International Database, which consists of over 1000 normal individuals who have undergone a complete neurophysiological and neuropsychological battery of tests [37]. IntegNeuro is used to establish the degree of cognitive impairment due to stroke, head injuries and dementias, and to evaluate treatment progress.

Instructions for each subtest are administered through headphones, and the system's touchscreen is used for providing answers by the person being examined. There is a high degree of standardisation as there is no human judgement by the administering Psychologist, whose role is limited to monitoring the test. 

 

Test of Variables of attention (TOVA)

TOVA test
TOVA test with microswitch
TOVA comparison
TOVA scores comparison

The Test of Variables of Attention (TOVA) is a highly sensitive, objective, and independent empirical measure to quantify the degree of impairment to the attention system and to measure the progress of treatment. The TOVA is a computer administered continuous performance task, which requires participants to press a specially designed micro switch whenever a "target" appears on the screen, and to refrain from pressing when a "non-target" appears. The scores are compared to an age appropriate database to produce standardised scores, which gives useful, objective information on four variables of attention:

  • Attention (the ability to concentrate and sustain mental effort)
  • Impulse control (the ability to inhibit impulsivenesss)
  • Processing speed (reaction time)
  • Distractibility (variability in reaction time)

 

Treatment of Post-Concussion Syndrome

A review paper in the October 2004 issue of Clinical EEG and Neuroscience concluded that QEEG was the most sensitive Neuroimaging tool for the assessment of post-concussion syndrome and that Neurotherapy had been shown to be the most promising treatment to date for post-concussion syndrome [33].

Medication, Counselling and Cognitive Rehabilitation

Medication may provide temporary relief from pain and counselling may help some persons understand the need to control their impulses and anger. However, there is no evidence in the literature that medication or cognitive rehabilitation can effectively restore the cognitive deficits or concentration in post-concussion syndrome.

Neurotherapy

People with attention deficits and MTBI tend to have an excess of slow-wave brain electrical activity and coherence abnormalities. Neurotherapy (EEG biofeedback) uses operant conditioning of the EEG to give patients audio/visual rewards for producing more normal patterns of brainwave activity. Since the 1970s studies have shown that, through Neurotherapy, patients can be taught to promote normal functioning in the brain by normalising dysfunctional brainwave patterns [33, 38-41]. A more recent improvement in Neurotherapy is in the use of QEEG to identify the specific brainwave patterns that need to be redressed [42-44]. Neurotherapy can also be used for improved  mood and concentration and enhancement of mental performance in persons with post-concussion syndrome. Look up the  major review of the literature published in October 2004 in Clinical Electroencephalography, a peer reviewed medical journal.

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